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TOP2A

Brief Information

Name:Topoisomerase (DNA) II alpha
Target Synonym:EC:5.6.2.2,EC 5.6.2.2,TOP2A,DNA topoisomerase 2-alpha,DNA topoisomerase II, alpha isozyme,DNA Topoisomerase II Alpha,Topoisomerase (DNA) II Alpha 170kDa,TOP2,DNA Topoisomerase (ATP-Hydrolyzing),DNA Topoisomerase II, 170 KD,EC 5.99.1.3,TP2A,DNA Gyrase
Number of Launched Drugs:1
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Approved

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By Conjugate:
Cat. No. Species Product Description Structure Purity Feature
TOA-H5117 Human Human TOP2A / TOP2 Protein, Tag Free
TOA-H5117-structure
TOA-H5117-sds
ACRO Quality

Synonym Name

TOP2A,TOP2,DNA topoisomerase 2-alpha,DNA topoisomerase II,alpha isozyme

Background

Clinical and Translational Updates

    Public Drug Information

    Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
    Etoposide phosphate BMY-40481 Approved Bristol-Myers Squibb Company Etopophos United States Lymphoma, Non-Hodgkin; Multiple Myeloma; Testicular Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Hodgkin Disease; Small Cell Lung Carcinoma Cheplapharm Arzneimittel Gmbh 1996-05-17 Lung Neoplasms; Neoplasms, Plasma Cell; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sarcoma, Ewing; Brain Neoplasms; Lymphoma, Follicular; Testicular Neoplasms; Lymphoma; Germinoma; Neoplasms, Gonadal Tissue; Breast Neoplasms; Lymphoma, Non-Hodgkin; Thrombocytopenia; Burkitt Lymphoma; Carcinoma, Non-Small-Cell Lung; Myelodysplastic-Myeloproliferative Diseases; Neoplasms, Germ Cell and Embryonal; Uterine Cervical Neoplasms; Neoplasm Metastasis; Neoplasms; Solid tumours; Ovarian Neoplasms; Kidney Neoplasms; Neutropenia; Plasmacytoma; Myelodysplastic Syndromes; Small Cell Lung Carcinoma; Hodgkin Disease; Leukemia; Myeloproliferative Disorders; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Immunoblastic; Multiple Myeloma; Central Nervous System Neoplasms; Adrenocortical Carcinoma; Neuroblastoma; Sarcoma Details

    Clinical Drug Information

    Name Research Code Research Phase Company Indications Clinical Trials
    Novobiocin Sodium Phase 1 Clinical Solid tumours; Neoplasms; Bacterial Infections Details

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