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Your Position: Home > Ephrin-B2

Ephrin-B2

Brief Information

Name:Ephrin-B2
Target Synonym:EPH-related receptor tyrosine kinase ligand 5,LERK-5,HTK ligand,HTK-L,EPLG5,HTKL,LERK5
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 1 Clinical

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Cat. No. Species Product Description Structure Purity Feature
EPN-H5259 Human Human Ephrin-B2 / EFNB2 Protein, Fc tag (MALS verified)
EPN-H5259-structure
EPN-H5259-sds
ACRO Quality

Part of Bioactivity data

EPN-H5259-MALS-HPLC
Ephrin-B2 MALS images

The purity of Human Ephrin-B2 Protein, Fc tag (Cat. No. EPN-H5259) is more than 90% and the molecular weight of this protein is around 82-101 kDa verified by SEC-MALS.

EPN-H5259-ELISA
Ephrin-B2 ELISA

Immobilized Nipah virus Glycoprotein, His Tag (Cat. No. GLN-N52H3) at 5 μg/mL (100 μL/well) can bind Human Ephrin-B2 Protein, Fc tag (Cat. No. EPN-H5259) with a linear range of 0.1-2 ng/mL (QC tested).

Protocol

Synonym Name

EFNB2

Background

Ephrin-B2 (EFNB2) is also known as EPH-related receptor tyrosine kinase ligand 5 (LERK-5) or HTK ligand (HTK-L), which belongs to the ephrin family. The ephrin-B (ENFB) class are transmembrane proteins implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. EFNB2 has been shown to interact with EPHA3 and EPHB1 in optic chiasm development. EFNB2 has also been shown to serve as a receptor for Hendra Virus and Nipah Virus, mediating entry into the cell during infection.

Clinical and Translational Updates

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
MTX-474 MTX-474 Phase 1 Clinical Mediar Therapeutics Inc Fibrosis Details

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