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| Name | Research Code | Research Phase | Company | First Brand Name | First Approved Country | First Indication | First Approved Company | First Approved Date | Indications | Clinical Trials |
|---|---|---|---|---|---|---|---|---|---|---|
| Glucosamine Hydrochloride | Approved | Dona, Xicil, Dolenio, Dona 200-S, Viartril-S | Mainland China | Osteoarthritis | Bright Future Pharmaceutical Laboratories Ltd | 2004-03-17 | Insulin Resistance; Chronic Periodontitis; Obesity; Osteoarthritis | Details | ||
| Charcoal | AST-120; MP-146 | Approved | Kureha Co | Kremezin, Zysa, Kremezin Fine Granules | Japan | Kidney Failure, Chronic | Mitsubishi Tanabe Pharma | 1991-10-04 | Inflammatory Bowel Diseases; Irritable Bowel Syndrome; Pouchitis; Hepatic Encephalopathy; Intestinal Fistula; Asthma; Gastroesophageal Reflux; Renal Insufficiency, Chronic; Kidney Failure, Chronic | Details |
| Mepacrine hydrochloride | CBL-0102; CBLC-102; Curaxin CBLC-102 | Approved | Bayer AG | Atebrin, Maladin, Atabrine, Tenicridine | Lupus Erythematosus, Systemic; Giardiasis; Leishmaniasis; Malaria | Bayer AG | 1932-01-01 | Creutzfeldt-Jakob Syndrome; Malaria; Carcinoma, Renal Cell; Giardiasis; Lupus Erythematosus, Systemic; Prostatic Neoplasms; Leishmaniasis | Details | |
| Anapsos | EQA-00 | Approved | Asac Pharmaceutical International | Psoriacen | Psoriasis; Dermatitis, Atopic | Asac Pharmaceutical International | 1972-01-01 | Psoriasis; Dermatitis, Atopic | Details | |
| Acetylaconitine | Approved | Mainland China | Pain | Shaanxi Xingbang Pharmacevtical Co Ltd | 1985-01-01 | Pain | Details | |||
| Andrographolide/Sodium Hydrogen Sulfite | Approved | Bacterial Infections | Details | |||||||
| Glucosamine Hydrochloride/Chondroitin sulfate | Approved | Details | ||||||||
| Glucosamine Hydrochloride/Indomethacin | Approved | Mainland China | Spondylitis, Ankylosing; Spondylosis; Periarthritis; Arthritis, Rheumatoid; Arthritis | null | 1995-01-01 | Spondylitis, Ankylosing; Arthritis, Rheumatoid; Periarthritis; Arthritis; Spondylosis | Details | |||
| Glucosamine Hydrochloride/Dermatan sulfate | Approved | Details | ||||||||
| Iguratimod | T-614 | Approved | Jiangsu Simcere Pharmaceutical Co Ltd | 艾得辛, Colvet, Iremod, Kolbet, Careram | Mainland China | Arthritis, Rheumatoid | Hainan Simcere Pharmaceutical Co Ltd | 2011-08-15 | Arthritis, Rheumatoid; Sjogren's Syndrome; Graft vs Host Disease | Details |
| Anvirzel | Approved | Nerium Biotechnology Inc, Ozelle Pharmaceuticals Inc | Anvirzel | Neoplasms | Details |
| Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
|---|---|---|---|---|---|
| Edasalonexent | CAT-1004 | Phase 3 Clinical | Catabasis Pharmaceuticals Inc | Diabetes Mellitus, Type 2; Muscular Dystrophy, Duchenne | Details |
| NF-kappa-B decoy oligonucleotide | MP-40; MP-41; MP-42; AMS-001; SI-3104; AMG-0101; AMG-0102; AMG-0103; S-414114 | Phase 3 Clinical | Anges Mg, Osaka University | Intervertebral Disc Degeneration; Dermatitis, Atopic | Details |
| RGN-259 | Thymosin beta4; Thymosin B4; Thymosin beta 4-16-38; Fx peptide; TB4 16-38; RGN-457; RGN-352; RGN-259; RGN-137; Tβ4; TB4; GBT-201; GBT-101 | Phase 3 Clinical | National Institutes Of Health | Myocardial Ischemia; Keratitis; ST Elevation Myocardial Infarction; Myocardial Infarction; Graft vs Host Disease; Sjogren's Syndrome; Dry Eye Syndromes; Epidermolysis Bullosa; Epidermolysis Bullosa, Junctional; Pressure Ulcer; Varicose Ulcer; Epidermolysis Bullosa Dystrophica; Diabetes Mellitus | Details |
| Dazdotuftide | TRS-01 | Phase 3 Clinical | Tarsius Pharma | Glaucoma; Uveitis, Anterior; Uveitis; Ocular inflammation | Details |
| Bardoxolone Methyl | RTA-402; NSC-713200 | Phase 3 Clinical | Kyowa Hakko Kirin Co Ltd, Reata Pharmaceuticals Inc | Liver Diseases; Melanoma; Kidney Failure, Chronic; Nephritis, Hereditary; Renal Insufficiency, Chronic; Hamman-Rich Syndrome; Lymphoma; Diabetic Nephropathies; Polycystic Kidney, Autosomal Dominant; Hepatic Insufficiency; Pulmonary Arterial Hypertension; Glomerulosclerosis, Focal Segmental; Solid tumours; Lung Diseases, Interstitial; Cryptogenic Organizing Pneumonia; Pancreatic Neoplasms; Idiopathic Pulmonary Fibrosis; Sarcoidosis; Coronavirus Disease 2019 (COVID-19); Diabetes Mellitus, Type 2; Idiopathic Interstitial Pneumonias; Glomerulonephritis, IGA; Hypertension, Pulmonary | Details |
| Hypochlorous Acid | PR-013; PR-022 | Phase 3 Clinical | Realm Therapeutics | Cataract; Virus Diseases; Coronavirus Disease 2019 (COVID-19); Endophthalmitis; Conjunctivitis, Allergic; Dermatitis, Atopic | Details |
| Bezisterim | HE-3286; NE-3107 | Phase 3 Clinical | Harbor Therapeutics, Biovie Inc | Diabetes Mellitus, Type 2; Brain Injuries, Traumatic; Insulin Resistance; Arthritis, Rheumatoid; Post-Acute COVID-19 Syndrome; Alzheimer Disease; Parkinson Disease; Colitis, Ulcerative | Details |
| Fluasterone | ST002; ST001; ST-001; HE-2500; 8354; ST-002 | Phase 2 Clinical | Harbor | Keratosis, Actinic; Cushing Syndrome; Metabolic Syndrome | Details |
| Nanocurcumin (Tehran University of Medical Sciences) | Phase 2 Clinical | Tehran University Of Medical Sciences | Neoplasms; Periapical Diseases | Details | |
| APPA | APPA; AKL-4; AKL-IV; APPA-1 | Phase 2 Clinical | AKL Research & Development Ltd | Osteoarthritis | Details |
| CKBA | CKBA | Phase 2 Clinical | BCY Pharm Co Ltd | Psoriasis; Vitiligo; Plaque psoriasis | Details |
| Manganese butoxyethyl pyridyl porphyrin | BMX-001; MnTnBuOE-2-PyP5+ | Phase 2 Clinical | Duke University | Head and Neck Neoplasms; Ovarian Neoplasms; Rectal Neoplasms; Glioblastoma; Astrocytoma; Glioma; Brain metastases; Carcinoma, Squamous Cell; Endometrial Neoplasms | Details |
| CBL-0137 | CX-137; CBL-0137; CBLC-137; Curaxin-CBL0137 | Phase 2 Clinical | Cleveland Biolabs Inc | Skin Melanoma; Hematologic Neoplasms; Solid tumours; Diffuse midline glioma; Neoplasms; Glioblastoma; Central Nervous System Neoplasms; Sarcoma; Osteosarcoma; Diffuse Intrinsic Pontine Glioma; Lymphoma; Melanoma | Details |
| Ornithine Phenylacetate | OP; L-OP; OCR-002; UCL-L1V; MNK-6105; MNK-6106 | Phase 2 Clinical | University College London | Liver Cirrhosis; Hepatic Encephalopathy | Details |
| Tepilamide fumarate | PPC-06; XP-23829 | Phase 2 Clinical | Xenoport Inc | Psoriasis | Details |
| Withaferin A | Phase 2 Clinical | UofL Health | Ovarian Neoplasms | Details | |
| Proximod | Phase 2 Clinical | Institue Of Materia Medica Chinese Academy Of Medical Science | Arthritis, Rheumatoid | Details | |
| YIV-906 | PHY-906; KD-018 | Phase 2 Clinical | Phytoceutica Inc | Liver Neoplasms; Rectal Neoplasms; Pancreatic Neoplasms; Diarrhea; Hepatitis B; Colorectal Neoplasms; Carcinoma, Hepatocellular | Details |
| GLS-1027 | GIT-27; VGX-1027 | Phase 2 Clinical | Geneone Life Science Inc | Pneumonia; Coronavirus Disease 2019 (COVID-19) | Details |
| Dimethylaminomicheliolide Fumarate | ACT-001 | Phase 2 Clinical | Tianjin Accendatech Technology Co Ltd | Solid tumours; Glioblastoma; Small Cell Lung Carcinoma; Optic Neuritis; Central Nervous System Neoplasms; Neuromyelitis Optica; Breast Neoplasms; Glioma; Brain metastases; Carcinoma, Non-Small-Cell Lung; Melanoma; Carcinoma, Hepatocellular | Details |
| Ascorbic Acid/Menadione | Phase 2 Clinical | Ic-Medtech Co, Summa Health System | Joint Diseases; Prostatic Neoplasms | Details | |
| LC-280126 | MIT-001; LC-280126; NecroX-7; LC28-0126 | Phase 2 Clinical | Lg Chemical Ltd | Hematologic Neoplasms; ST Elevation Myocardial Infarction; Squamous Cell Carcinoma of Head and Neck; Multiple Myeloma; Lymphoma; Stomatitis | Details |
| Ginsenoside C-K | IH-901; Compound K | Phase 1 Clinical | Rohto, Il-Hwa, Zhejiang Hisun Pharmaceutical Co Ltd, Fudan University, State Pharmaceutical Administration of Shanghai Institute of Pharmaceutical Industry | Arthritis, Rheumatoid | Details |
| ORYN-1001 | ORTD-1; ORYN-1001 | Phase 1 Clinical | Oryn Therapeutics Llc | Coronavirus Disease 2019 (COVID-19); Arthritis, Rheumatoid | Details |
| CKD-712 | CKD-712 | Phase 1 Clinical | Chong Kun Dang Pharmaceutical Corp | Sepsis | Details |
| LH-025 | LH-025 | Phase 1 Clinical | Dr August Wolff | Colitis, Ulcerative | Details |
| Xempritolimod | KMRC-011; KMRC011; CNT-101; CNT-102 | Phase 1 Clinical | Korea Institute Of Industrial Technology | Graft vs Host Disease; Neoplasms; Acute Radiation Syndrome; Stomatitis | Details |
| DEN-181 | DEN-181; CurcusomeRA; CurcusomeTMRA | Phase 1 Clinical | Dendright | Arthritis, Rheumatoid | Details |
| ILB-202 | ILB-202; ILB202 | Phase 1 Clinical | Ilias Biologics Inc | Acute Kidney Injury; Intraoperative Complications | Details |
| SFA-001 | SFA-001; SFA-001N | Phase 1 Clinical | Temple University | Metabolic Dysfunction-Associated Steatotic Liver Disease; Fibrosis | Details |
| TML-6 | TML-6 | Phase 1 Clinical | Merry Life Biomedical Co Ltd | Alzheimer Disease | Details |
| RHN-002 | RHN-002; RHN002 | Phase 1 Clinical | RH Nanopharmaceuticals LLC | Pain, Postoperative; Anemia, Sickle Cell | Details |
| RHN-001 | RHN-001; RHN001 | Phase 1 Clinical | RH Nanopharmaceuticals LLC | Details | |
| Hypochlorous Acid/Acetic Acid | SS0350; SS-0350 | Phase 1 Clinical | Softox Solutions As | Leg Ulcer; Varicose Ulcer | Details |
| SHetA2 | Phase 1 Clinical | The University Of Oklahoma | Solid tumours | Details | |
| TLZ-16-CL | TLZ-16-CL | Phase 1 Clinical | Beijing Taizhou Lize Pharmaceutical Technology Co Ltd | Substance Withdrawal Syndrome; Cocaine-Related Disorders | Details |
| OP-101 | OP-101 | Phase 1 Clinical | Ashvattha Therapeutics | Adrenoleukodystrophy; Coronavirus Disease 2019 (COVID-19) | Details |
| Anatabine citrate | RCP-006 | Clinical | Rock Creek, Roskamp Institute | Smoking Cessation; Thyroiditis, Autoimmune; Tobacco Use Disorder; Alzheimer Disease; Inflammation | Details |
| Tarenflurbil spraygel (MIKA Pharma) | Clinical | Galen Ltd, Mika Pharma Gmbh | Pain; Arthritis, Rheumatoid; Skin Diseases; Inflammation; Dermatitis, Atopic | Details |
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