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| Cat. No. | Species | Product Description | Structure | Purity | Feature |
|---|---|---|---|---|---|
| CHEK-ATP213 | Human | HEK293/Human SSTR2 Stable Cell Line | |||
| SS2-HF2G3 | Human | Fluorescent Human SSTR2 Full Length Protein (VLP) |
|
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| SS2-H5216 | Human | Human SSTR2 Full Length Protein (VLP) |
|
Expression analysis of human SSTR2 on HEK293/Human SSTR2 Stable Cell Line by FACS.
Cell surface staining was performed on HEK293/Human SSTR2 Stable Cell Line or negative control cell using anti-human SSTR2 antibody followed by staining with PE anti-human IgG Fc Antibody.
Expression analysis of Flag tag on HEK293/Human SSTR2 Stable Cell Line by FACS.
Cell surface staining was performed on HEK293/Human SSTR2 Stable Cell Line or negative control cell using PE-Cy7-labeled anti-Flag antibody.
Immobilized Human SSTR2 Full Length Protein-VLP (Cat. No. SS2-H5216) at 5 μg/mL (100 μL/well) can bind Anti-SSTR2 Antibody, Human IgG1 with a linear range of 0.3-5 ng/mL (QC tested).
| Name | Research Code | Research Phase | Company | First Brand Name | First Approved Country | First Indication | First Approved Company | First Approved Date | Indications | Clinical Trials |
|---|---|---|---|---|---|---|---|---|---|---|
| Pasireotide Pamoate | Approved | Novartis Pharma Ag | Signifor lar | United States | Acromegaly | Recordati Rare Diseases Inc | 2014-12-15 | Acromegaly; Gigantism; Cushing Syndrome; Carcinoid Tumor; Neuroendocrine Tumors; Pituitary ACTH Hypersecretion; Meningioma | Details | |
| Lutetium (177Lu) oxodotreotide | Lu-DOTATATE; Lutetium (177Lu) DOTA-TATE; 177Lu-DOTATATE; [Lu-177]-DOTATATE; AAA-601; F-1515; XTR-008; [177Lu]Lu-DOTA-TATE | Approved | Advanced Accelerator Applications Sa | Lutathera | EU | Neuroendocrine Tumors | Advanced Accelerator Applications Sa | 2017-09-26 | Prostatic Neoplasms; Carcinoid Heart Disease; Meningioma; Paraganglioma; Gastroenteropancreatic neuroendocrine tumor; Metastatic breast cancer; Lung Neoplasms; Carcinoma, Neuroendocrine; Pituitary Neoplasms; Medullary thyroid cancer (MTC); Neuroblastoma; Liver Neoplasms; Breast Neoplasms; Neuroendocrine Tumors; Malignant Carcinoid Syndrome; Pancreatic neuroendocrine tumors (pNET); Pancreatic Neoplasms; Adenoma, Islet Cell; Bronchial Neoplasms; Carcinoid Tumor; Pheochromocytoma; Leiomyosarcoma | Details |
| Vapreotide Acetate | RC-160; BMY-41606 | Approved | Debiopharm Group | Sanvar, Docrised, Sanvar IR, Sanvar SR | Acromegaly; Pancreatic Neoplasms; Hypertension, Portal; Neuroendocrine Tumors; Hemorrhage; Diarrhea; Intraoperative Complications; Postoperative Complications; Esophageal and Gastric Varices; Crohn Disease | Details | ||||
| Pasireotide Diaspartate | SOM-230; SOM-230C; SOM-320 | Approved | Novartis Pharma Ag | Signifor, 丝尼芬 | EU | Cushing Syndrome | Recordati Rare Diseases Inc | 2012-04-24 | Hyperinsulinism; Cysts; Uveal melanoma; Multiple Myeloma; Prostatic Neoplasms; Medullary thyroid cancer (MTC); Alcoholism; Nelson Syndrome; Pituitary Neoplasms; Prostatic Neoplasms, Castration-Resistant; Thyroid Neoplasms; Thymoma; Cluster Headache; Gastroenteropancreatic neuroendocrine tumor; Carcinoma, Hepatocellular; Gastrointestinal Neoplasms; Prolactinoma; Meningioma; Pancreatic Neoplasms; ACTH Syndrome, Ectopic; Congenital Hyperinsulinism; Cushing Syndrome; Dumping Syndrome; Carcinoid Tumor; Renal Insufficiency; Insulinoma; Hypoglycemia; Acromegaly; Liver Cirrhosis; Neoplasms; Hormone-Resistant Prostate Neoplasms; Small Cell Lung Carcinoma; Adenoma, Islet Cell; Pituitary ACTH Hypersecretion; Neuroendocrine Tumors | Details |
| Ga-68 Edotreotide | SMT-487; [68Ga]DOTATOC; 90Y-DOTATOC | Approved | Advanced Accelerator Applications Sa | SomaKit TOC, Gallium Dotatoc Ga 68, TOCscan | EU | Diagnostic agents; Pancreatic neuroendocrine tumors (pNET); Neuroendocrine Tumors | Advanced Accelerator Applications Sa | 2016-12-08 | Medulloblastoma; Multiple Endocrine Neoplasia Type 1; Carcinoid Tumor; Pancreatic neuroendocrine tumors (pNET); Neuroendocrine Tumors; Neuroblastoma; Pituitary Neoplasms; Diagnostic agents; Paraganglioma; Meningioma; von Hippel-Lindau Disease; Somatostatinoma | Details |
| Gallium (68Ga) oxodotreotide | 68Ga-DOTA-TATE; 68-Ga-DOTA-TATE | Approved | Advanced Accelerator Applications Sa | Netspot | United States | Neuroendocrine Tumors | Aaa Usa Inc | 2016-06-01 | Carcinoid Tumor; Pheochromocytoma; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Neuroendocrine Tumors; Prostatic Neoplasms; Carcinoma, Neuroendocrine; Thyroid Neoplasms; Carcinoma, Hepatocellular; von Hippel-Lindau Disease; Paraganglioma | Details |
| Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
|---|---|---|---|---|---|
| Paltusotine | CRN-00808 | Phase 3 Clinical | Crinetics Pharmaceuticals Inc | Acromegaly; Malignant Carcinoid Syndrome; Neuroendocrine Tumors | Details |
| Lutetium-177 labelled edotreotide | ITM-11 | Phase 3 Clinical | Universitaetsspitals Basel, Itm Solucin Gmbh | Solid tumours; Pancreatic neuroendocrine tumors (pNET); Neuroendocrine Tumors; Central Nervous System Neoplasms; Thymus Neoplasms; Carcinoma, Neuroendocrine; Lung Neoplasms; Lymphoma; Gastroenteropancreatic neuroendocrine tumor | Details |
| Actinium-225 Dotate | RYZ-101; 225Ac-DOTATATE | Phase 3 Clinical | RayzeBio Inc | Carcinoid Tumor; Small Cell Lung Carcinoma; Neuroendocrine Tumors; Multiple Myeloma; Breast Neoplasms; Metastatic breast cancer; Gastroenteropancreatic neuroendocrine tumor | Details |
| Lutetium-177 DOTA satoreotide | [177Lu]LuSSO110; 177Lu-DOTA- JR11; 177Lu-satoreotide; 177Lu-IPN01072; 177Lu-IPN-1072; 177Lu SSO 110; OPS-201; 177LU-OPS 201 | Phase 2 Clinical | OctreoPharm Sciences GmbH | Small Cell Lung Carcinoma; Pancreatic neuroendocrine tumors (pNET); Breast Neoplasms; Meningioma | Details |
| Nendratareotide uzatansine | BTP-277; PEN-221 | Phase 2 Clinical | Tarveda Therapeutics Inc | Small Cell Lung Carcinoma; Neuroendocrine Tumors; Carcinoma, Neuroendocrine | Details |
| Yttrium 90-labelled edotreotide | SMT-487-[90Y]; DOTATOC-[90Y] | Phase 2 Clinical | The University Of Iowa, Novartis Pharma Ag | Solid tumours; Medulloblastoma; Skin Melanoma; Pheochromocytoma; Carcinoid Tumor; Adenoma, Islet Cell; Neoplasms; Central Nervous System Neoplasms; Neuroendocrine Tumors; Neuroblastoma; Breast Neoplasms; Sarcoma; Brain Neoplasms; Lymphoma; Lung Neoplasms; Meningioma | Details |
| ZT-01 | ZT 01; ZT-01 | Phase 2 Clinical | Tulane University, York University, University Of Toronto, Toronto | Diabetes Mellitus, Type 1; Hypoglycemia | Details |
| Re-188 P 2045 | P2045; BAY-865284; Rhenium-188 P2045; Re-188 P 2045; Rh-188 P2045; Rhenium-188-P-2045 | Phase 2 Clinical | Bayer AG | Neoplasm Recurrence, Local; Small Cell Lung Carcinoma; Neuroendocrine Tumors; Lung Neoplasms; Carcinoma, Small Cell; Carcinoma, Non-Small-Cell Lung | Details |
| [203-Pb] VMT-NET | [203-Pb] VMT-NET | Phase 2 Clinical | Perspective Therapeutics Inc | Head and Neck Neoplasms; Pheochromocytoma; Carcinoma, Renal Cell; Small Cell Lung Carcinoma; Neuroendocrine Tumors; Paraganglioma | Details |
| 64Cu-SarTate | Phase 2 Clinical | Clarity Pharmaceuticals Ltd, University Of Melbourne | Neuroendocrine Tumors; Neuroblastoma; Meningioma | Details | |
| 68Ga-NOTA-3PTATE-RGD | 68Ga-NOTA-3PTATE-RGD; 68Ga-NOTA-3P-TATE-RGD | Phase 1 Clinical | Peking Union Medical College Hospital | Neuroendocrine Tumors; Lung Neoplasms; Meningioma | Details |
| [225Ac]Ac-DOTATATE | Phase 1 Clinical | Beijing Xiantong International Technology Co Ltd | Neuroendocrine Tumors | Details | |
| [99mTc]Tc-TECANT1 | Phase 1 Clinical | Ljubljana University Medical Centre, Medical University Of Innsbruck, Narodowe Centrum Badan Jadrowych, Jagiellonian University Sylff Fellows Association | Neuroendocrine Tumors | Details | |
| 161Tb-DOTA-LM3 | 161Tb-DOTA-LM3 | Phase 1 Clinical | University Hospital Basel | Neuroendocrine Tumors; Gastroenteropancreatic neuroendocrine tumor | Details |
| 44Sc-edotreotide | 44Sc-edotreotide; 44Sc-DOTA-[3-Tyr]-octreotide; Sc44-DOTATOC | Clinical | Zentralklinik Bad Berka | Diagnostic agents | Details |
| 225AcDOTA-LM3 | 225AcDOTA-LM3 | Clinical | CURANOSTICUM Wiesbaden-Frankfurt | Pancreatic neuroendocrine tumors (pNET) | Details |
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