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| Project Name | Project Stage | Molecule Type | Host Species | Therapeutic Area | Indications |
| GDF15 mAb - 01 | PCC | Metabolism | Solid tumor,Cancer cachexia |
| Cat. No. | Species | Product Description | Structure | Purity | Feature |
|---|---|---|---|---|---|
| CEA-C077 | Human | ClinMax™ Human GDF-15 ELISA Kit | |||
| GD5-H81Q3 | Human | Biotinylated Human GDF-15 / MIC-1 Protein, His,Avitag™ |  |
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| GD5-M5149 | Mouse | Mouse GDF-15 / MIC-1 Protein, His Tag |  |
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| GD5-H82F9 | Human | Biotinylated Human GDF-15 / MIC-1 Protein, Avitag™, Fc Tag (MALS verified) |  |
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| GD5-C5148 | Cynomolgus | Cynomolgus GDF-15 / MIC-1 Protein, His Tag |  |
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| GD5-H5269 | Human | Human GDF-15 / MIC-1 Protein, Fc Tag (MALS verified) |  |
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| GD5-H5149 | Human | Human GDF-15 / MIC-1 Protein, His Tag |  |
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Immobilized Mouse GDF-15, His Tag (Cat. No. GD5-M5149) at 1 μg/mL (100 μL/well) can bind Human GFR alpha-like, Fc Tag (Cat. No. GFE-H5259) with a linear range of 0.3-10 ng/mL (QC tested).
The purity of Biotinylated Human GDF-15, Avitag, Fc Tag (Cat. No. GD5-H82F9) is more than 85% and the molecular weight of this protein is around 80-95 kDa verified by SEC-MALS.
| Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
|---|---|---|---|---|---|
| NGM-120 | NGM-120 | Phase 2 Clinical | Ngm Biopharmaceuticals Inc | Ovarian Neoplasms; Squamous Cell Carcinoma of Head and Neck; Esophageal Neoplasms; Stomach Neoplasms; Anorexia; Pancreatic Neoplasms; Urinary Bladder Neoplasms; Prostatic Neoplasms, Castration-Resistant; Prostatic Neoplasms; Colorectal Neoplasms; Cachexia; Melanoma; Carcinoma, Non-Small-Cell Lung | Details |
| Visugromab | CTL-002 | Phase 2 Clinical | CatalYm GmbH | Solid tumours; Urinary Bladder Neoplasms | Details |
| Ponsegromab | PF-06946860 | Phase 2 Clinical | Pfizer Inc | Ovarian Neoplasms; Heart Failure; Fatigue; Pancreatic Neoplasms; Anorexia; Feeding and Eating Disorders; Prostatic Neoplasms; Breast Neoplasms; Colorectal Neoplasms; Cachexia; Carcinoma, Non-Small-Cell Lung | Details |
| GDF15 agonist (Lilly) | Phase 1 Clinical | Eli Lilly And Company | Diabetes Mellitus | Details | |
| NN-9215 | Human-GDF15; MIC-1; NN-9215; LA-GDF15 | Phase 1 Clinical | Novo Nordisk A/S | Obesity | Details |
| CIN-109 | CIN-109; JNJ-9090 | Phase 1 Clinical | Janssen Sciences Ireland Unlimited Company | Obesity | Details |
| MBL-949 | MBL-949 | Phase 1 Clinical | Novartis Pharma Ag | Obesity; Diabetes Mellitus | Details |
| AV-380 | AV-380 | Phase 1 Clinical | Aveo Pharmaceuticals Inc | Cachexia | Details |
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