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This protein carries an Avi tag (Avitag™) at the N-terminus, followed by a polyhistidine tag.
The protein has a calculated MW of 25.3 kDa. The protein migrates as 28-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
>90% as determined by SDS-PAGE.
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
Biotinylated Mouse IL-6, Avitag,His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Biotinylated Mouse IL-6, Avitag,His Tag (Cat. No. IL6-M82Q7) at 1 μg/mL (100 μL/well) on streptavidin precoated (STN-N5116) can bind Mouse IL-6 R alpha Protein, Fc Tag (Cat. No. ILR-M5255) with a linear range of 0.3-2 ng/mL (QC tested).
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English Name | Research Code | Research Phase | Company | First Brand Name | First Approved Country | First Indication | First Approved Company | First Approved Date | Indications | Clinical Trials |
---|---|---|---|---|---|---|---|---|---|---|
Lenalidomide | CC-5013; IMiD-3; ENMD-0997; STAR-LLD; IMID-5013; CDC-5013; CDC-501 | Approved | Celgene Corp | Revimid (former Brand Name), 瑞复美, Revlimid, Leavdo, Zelvina | United States | Myelodysplastic Syndromes | Bristol Myers Squibb Srlcompany | 2005-12-27 | Lymphoma, T-Cell, Peripheral; Lymphoma, B-Cell, Marginal Zone; Solid tumours; Bone Marrow Neoplasms; Kidney Neoplasms; Leukemia, Myeloid; Leukemia; Intestinal Neoplasms; Craniopharyngioma; Optic Nerve Glioma; Leukemia, Promyelocytic, Acute; Ovarian Neoplasms; Medulloblastoma; Ependymoma; Immunoproliferative Small Intestinal Disease; Leukemia, Erythroblastic, Acute; Hematologic Diseases; Liver Neoplasms; Plaque, Amyloid; Anemia; Pain; Paraproteinemias; Polycythemia Vera; Anemia, Refractory, with Excess of Blasts; Rhabdoid Tumor; Leukemia, Hairy Cell; Lymphoma, Large B-Cell, Diffuse; Myelodysplastic Syndromes; Leukemia, Myelomonocytic, Chronic; Leukemia-Lymphoma, Adult T-Cell; Plasmacytoma; Hodgkin Disease; Graft vs Host Disease; Glioblastoma; Neoplasms; Blood Protein Disorders; Nerve Degeneration; Anemia, Refractory; Hypothalamic Neoplasms; Leukemia, Myelomonocytic, Acute; Pancreatic Neoplasms; Lymphomatoid Granulomatosis; Smoldering Multiple Myeloma; Multiple Myeloma; Urinary Bladder Neoplasms; Central Nervou | Details |
Luminol sodium | MP-1032 | Approved | Selvim, Metrio | Psoriasis; Immune System Diseases | null | 1997-01-01 | Coronavirus Disease 2019 (COVID-19); Immune System Diseases; Psoriasis; Plaque psoriasis | Details | ||
Pomalidomide | CDC-394; CC-4047; IMiD-1; IMID-4047 | Approved | Celgene Corp | Pomalyst, Imnovid, Actimid, Pomalyst/Imnovid, 安跃 | United States | Multiple Myeloma | Bristol-Myers Squibb Company | 2013-02-08 | Lung Diseases, Interstitial; Neurofibromatosis 1; Atypical Squamous Cells of the Cervix; Sarcoma, Kaposi; Anemia, Sickle Cell; Lymphoma, Non-Hodgkin; Carcinoma, Small Cell; Glioma; Waldenstrom Macroglobulinemia; Primary Myelofibrosis; Prostatic Neoplasms; Thrombocytosis; Sarcoma; Central Nervous System Neoplasms; Pulmonary Fibrosis; Medulloblastoma; Multiple Myeloma; Pancreatic Neoplasms; Hodgkin Disease; Plasmacytoma; Myeloproliferative Disorders; Immunoglobulin Light-chain Amyloidosis; Graft vs Host Disease; Scleroderma, Systemic; Renal Insufficiency; Polycythemia Vera; Bone Marrow Neoplasms; Solid tumours; Optic Nerve Glioma | Details |
Siltuximab | cCLB-8; CNTO-328 | Approved | Johnson & Johnson | Sylvant | United States | Multicentric Castleman's Disease (MCD) | Eusa Pharma | 2014-04-23 | Immunoglobulin Light-chain Amyloidosis; Leukemia, Large Granular Lymphocytic; Thrombocytopenia; Lung Neoplasms; Lymphoma, Non-Hodgkin; Primary Myelofibrosis; Castleman Disease; Colorectal Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Neoplasms, Plasma Cell; Prostatic Neoplasms; Multicentric Castleman's Disease (MCD); Monoclonal Gammopathy of Undetermined Significance; Lung Diseases; Multiple Myeloma; Respiratory Distress Syndrome, Adult; Bone Marrow Neoplasms; Pancreatic Neoplasms; Myelodysplastic Syndromes; Psychotic Disorders; Respiratory Tract Diseases; Smoldering Multiple Myeloma; Polycythemia Vera; Carcinoma, Renal Cell; Pneumonia; Schizophrenia; Diabetes Mellitus, Type 1; Ovarian Neoplasms; Cytokine Release Syndrome; Head and Neck Neoplasms; Respiratory Tract Infections; Kidney Neoplasms | Details |
Andrographolide/Sodium Hydrogen Sulfite | Approved | Bacterial Infections | Details | |||||||
Thalidomide | NSC-66847; NSC-527179; K-17; FPF-300; FPF300 | Approved | Celgene Corp | Talizer, Thalidomide Celgene, Thalidomide Pharmion, Synovir, Thalomid, Thaled | Mainland China | Leprosy, Lepromatous; Multiple Myeloma | Changzhou Pharmaceutical Factory | 1982-01-01 | Xerostomia; Colorectal Neoplasms; Neuroectodermal Tumors, Primitive; Prostatitis; Primary Myelofibrosis; Osteosarcoma; Cholangitis, Sclerosing; Lymphoma, Mantle-Cell; Lymphoma, Follicular; Adenocarcinoma, Clear Cell; Carcinoma, Adenosquamous; Epilepsy; Erythema Nodosum; Sarcoma; HIV Wasting Syndrome; Pancreatitis, Chronic; Sarcoma, Ewing; Arachnoiditis; Gastrointestinal Hemorrhage; Retinoblastoma; Prostatic Neoplasms; Endometriosis; Lung Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Vascular Malformations; Myelodysplastic-Myeloproliferative Diseases; Mycobacterium avium-intracellulare Infection; Amyotrophic Lateral Sclerosis; Carcinoma, Hepatocellular; Burning Mouth Syndrome; Stomatitis; Neoplasm Metastasis; Appendiceal Neoplasms; Tuberculosis; Lymphoma, Non-Hodgkin; Angiodysplasia; Pelvic Pain; Glioma; Waldenstrom Macroglobulinemia; Leprosy, Lepromatous; Endometrial Neoplasms; Uterine Neoplasms; Anemia, Sideroblastic; Ovarian Neoplasms; Gastric Antral Vascular Ectasia; Lupus Erythematosus, Discoid; Carc | Details |
English Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
---|---|---|---|---|---|
Ensereptide | PXL-01 | Phase 3 Clinical | Promore Pharma | Tissue Adhesions; Post-surgical adhesions; Cicatrix | Details |
Olokizumab | CDP-6038; Anti-IL6-UCB | Phase 3 Clinical | Ucb | Arthritis, Rheumatoid; Coronavirus Disease 2019 (COVID-19); Lung Diseases, Interstitial; Arthritis; Crohn Disease | Details |
Efprezimod alfa | CD24-Fc; HAS-CD24; CD24-Fc-IgG; MK-7110; MK7110 | Phase 3 Clinical | Oncoimmune Inc | HIV Infections; Hematopoietic stem cell transplantation (HSCT); Solid tumours; Leukemia; Graft vs Host Disease; Coronavirus Disease 2019 (COVID-19); Myelodysplastic Syndromes; Dyslipidemias; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Leukemia, Myeloid, Acute; Melanoma | Details |
Ziltivekimab | COR-001; NN6018 | Phase 3 Clinical | Astrazeneca Plc | Heart Failure; Atherosclerosis; Anemia; Myocardial Infarction; Cardiovascular Diseases; Renal Insufficiency, Chronic; Inflammation; Systemic Inflammatory Response Syndrome | Details |
Clazakizumab | BMS-645429; ALD518-003; ALD-518; CSL300; BMS-945429; CSL-300 | Phase 3 Clinical | Alder Biopharmaceuticals | Cardiovascular Diseases; Stomatitis; Carcinoma, Non-Small-Cell Lung; Crohn Disease; Diabetes Mellitus; Kidney Failure, Chronic; Cachexia; Asthma; Arthritis, Psoriatic; Plaque, Atherosclerotic; Rejection of organ transplantation; Graft vs Host Disease; Arthritis, Rheumatoid; Fatigue; Coronavirus Disease 2019 (COVID-19); Atherosclerosis; Myocardial Infarction | Details |
Tabirafusp tedromer | KSI-501ABC; KSI-501 | Phase 3 Clinical | Kodiak Sciences Inc | Retinal Diseases; Wet Macular Degeneration; Diabetic macular oedema; Uveitis | Details |
Bezisterim | HE-3286; NE-3107 | Phase 3 Clinical | Harbor Therapeutics, Biovie Inc | Diabetes Mellitus, Type 2; Brain Injuries, Traumatic; Insulin Resistance; Arthritis, Rheumatoid; Post-Acute COVID-19 Syndrome; Alzheimer Disease; Parkinson Disease; Colitis, Ulcerative | Details |
Vamikibart | RO-7200220; RG-6179; EBI-031 | Phase 3 Clinical | Sesen Bio Inc | Macular Edema; Diabetic macular oedema | Details |
Sodium Hypochlorite | Phase 3 Clinical | Cystic Fibrosis; Pulpitis; Infections; Pain; Pain, Postoperative; Fibrosis; Dental Pulp Necrosis | Details | ||
PF-04236921 | PF-04236921; TOUR006; TOUR-006; PF-4236921 | Phase 2 Clinical | Pfizer Inc | Arthritis, Rheumatoid; Graves Ophthalmopathy; Lupus Erythematosus, Systemic; Cardiovascular Diseases; Renal Insufficiency, Chronic; Crohn Disease | Details |
Sirukumab | BA-003; CNTO-136 | Phase 2 Clinical | Glaxosmithkline Plc, Johnson & Johnson Innovative Medicine | Depressive Disorder, Major; Giant Cell Arteritis; Arthritis, Rheumatoid; Lupus Erythematosus, Cutaneous; Coronavirus Disease 2019 (COVID-19); Lupus Nephritis; Polymyalgia Rheumatica; Lupus Erythematosus, Systemic; Asthma | Details |
KSI-101 | KSI-501P; KSI-101 | Phase 2 Clinical | Kodiak Sciences Inc | Macular Edema | Details |
Anti-interleukin-6 receptor monoclonal antibody (Biocad) | Phase 2 Clinical | BIOCAD JSC | Autoimmune Diseases | Details | |
Isomyosamine | MYMD-1 | Phase 2 Clinical | Mymd Pharmaceuticals Inc | Anxiety; Frailty; Hashimoto Disease; Depression; Coronavirus Disease 2019 (COVID-19); Arthritis, Rheumatoid; Healthy Aging; Inflammation; Sarcopenia | Details |
FB-704A | FB-704; FB-704A | Phase 2 Clinical | Fountain Biopharma Inc | Arthritis, Rheumatoid; Asthma | Details |
Gerilimzumab | GB-224; RYI-008; ARGX-109 | Phase 1 Clinical | Argenx Se | Arthritis, Rheumatoid | Details |
MEDI-5117 | WBP-216; MEDI-5117 | Phase 1 Clinical | Wuxi Apptec Co Ltd, Medimmune | Arthritis, Rheumatoid | Details |
Tocilizumab biosimilar (Mycenax Biotech) | Phase 1 Clinical | Mycenax Biotech Inc | Arthritis, Rheumatoid | Details | |
SCD-153 | SCD-153 | Phase 1 Clinical | Sun Pharma Advanced Research Company Ltd, Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Johns Hopkins University | Alopecia Areata | Details |
NEX-20A | NEX-20A | Phase 1 Clinical | Nanexa AB | Multiple Myeloma | Details |
Luxeptinib | CG026806; CG-806; CG’806; CG-026806 | Phase 1 Clinical | Crystalgenomics Inc | Hematologic Neoplasms; Myelodysplastic Syndromes; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Follicular; Lymphoma, Non-Hodgkin; Leukemia, Myeloid, Acute; Leukemia, Lymphocytic, Chronic, B-Cell | Details |
Wogonin | Shandong Buchang Pharmaceuticals Co Ltd, Hefei Cosource Medicine Technology, Daewoong Pharmaceutical Co Ltd, China Pharmaceutical University | Details |
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