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Virus-like particles(VLPs) are formed by self-assembly of envelop/capsid proteins from viruses. Membrane Proteins can be constituted in-situ with VLPs produced from HEK293 cell cultures. These VLPs concentrate conformationally intact membrane proteins directly on the cell surface and produce soluble, high-concentration proteins perfect for immunization and antibody screening.
The VLPs provide the display of properly folded membrane proteins in their native cellular membrane in a compact size of 100~300 nm diameter (similar to the size of most viruses) making it optimal targets for dendritic cells in vivo and surface attachment for phage display.
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GMP grade cytokines, reagents for cell activation, gene edition, DNA/RNA removal, etc. Particularly focus on product design, quality control and solution-based support to link each phase of your cell and gene therapy journey.
Full length multi-pass TPs with stabilized structure and high bioactivity for immunization, antibody screening, cell based assay and CAR detection, including hot CD20, Claudin 18.2, CD133, GPRC5D,CCR8, CCR5, etc.
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English Name | Research Code | Research Phase | Company | First Brand Name | First Approved Country | First Indication | First Approved Company | First Approved Date | Indications | Clinical Trials |
---|---|---|---|---|---|---|---|---|---|---|
Cannabidiol/Dronabinol | THC-5; delta-9-THC/CBD; MPL-001; MPL-005; GW-1000; KL16-012; BOL-DP-o-04; GW-1000-02; PPP-001; MGC-ODT | Approved | Gw Pharmaceuticals | Sativex, Qixleef | Canada | Muscle Spasticity; Neuralgia; Cancer Pain; Chronic Pain; Multiple Sclerosis | null | 2005-04-01 | Dementia; Panic Disorder; Phobia, Social; Neuralgia, Postherpetic; Huntington Disease; Reflex Sympathetic Dystrophy; Tourette Syndrome; Muscle Spasticity; Malnutrition; Sciatica; Acute Pain; Neuromyelitis Optica; Arthritis, Psoriatic; Neuralgia; Urinary Bladder, Overactive; Back Pain; Osteoarthritis, Knee; Hepatic Insufficiency; Stress Disorders, Post-Traumatic; Healthy Aging; Hidradenitis Suppurativa; Agoraphobia; Drug Resistant Epilepsy; Renal Insufficiency, Chronic; Social Behavior; Corticobasal degeneration; Cerebral Palsy; Low Back Pain; Agitation; Sleep Initiation and Maintenance Disorders; Peripheral Nervous System Diseases; Genital Diseases, Male; Pain; Chronic Pain; Depression; Depressive Disorder, Major; Marijuana Abuse; Marijuana Use; Spasm; Squamous Cell Carcinoma of Head and Neck; Cancer Pain; Renal Insufficiency; Migraine Disorders; Spinal Cord Injuries; Neoplasms; Arthritis, Rheumatoid; Neck Pain; Diabetic Neuropathies; Sleep Wake Disorders; Opioid-Related Disorders; Essential Tremor; Anorexia; | Details |
Cannabidiol | AVCN-583601; GLA-015; BTX-1503; BTX-1801; BTX-1702; LYT-310; RAD011; PBX-1308; RAD-011; BRCX-014; RLS-103; GWP-42003; GWP-42003-P; BOL-DP-o-05; GW-42003; BTX-1204; ZYN-002; PTL-101; CHI-902; APH-1501 | Approved | Gw Pharmaceuticals Plc | Epidiolex, Epidyolex, Zygel, Cannepil | United States | Epilepsies, Myoclonic; Lennox Gastaut Syndrome | null | 2018-06-25 | Tobacco Smoking; Migraine Disorders; Peripheral Nervous System Diseases; Acne Vulgaris; HIV Infections; Ovarian Neoplasms; Sleep Initiation and Maintenance Disorders; Facial Pain; Substance-Related Disorders; Marijuana Smoking; Tobacco Use Cessation; Seizures; Tuberous Sclerosis; Pain; Schizophrenia; Chronic Pain; Marijuana Use; Anxiety; Rett Syndrome; Appetitive Behavior; Autism Spectrum Disorder; Marijuana Abuse; Brain Injuries, Traumatic; Depression; Alcoholic Intoxication; Inflammatory Bowel Diseases; Fatty Liver; Child Behavior Disorders; Diabetes Mellitus, Type 2; Spinal Cord Injuries; Muscle injury; Neoplasms; Psychotic Disorders; Opioid-Related Disorders; Diabetic Neuropathies; Coronavirus Disease 2019 (COVID-19); Musculoskeletal Pain; Anxiety Disorders; Sleep Wake Disorders; Graft vs Host Disease; Blepharospasm; Dyspepsia; Arthritis, Rheumatoid; Hyperalgesia; Chronic Urticaria; Hoarding Disorder; Bipolar Disorder; Pancreatic Neoplasms; Brain Diseases; Dysmenorrhea; Sturge-Weber Syndrome; Memory; Mult | Details |
English Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
---|---|---|---|---|---|
Ajulemic acid | HU-239; CPL-7075; CT-3; JBT-101; DMH-THC-11-OIC; DMH-11C; IP-751 | Phase 3 Clinical | Corbus Pharmaceuticals Holdings Inc | Lupus Vulgaris; Cystic Fibrosis; Dermatomyositis; Lupus Erythematosus, Systemic; Scleroderma, Diffuse | Details |
Dronabinol(AXIM Biotechnologies) | Phase 3 Clinical | Axim Biotechnologies Inc | Neoplasms; Nutrition Disorders; Child Nutrition Disorders; Vomiting; Nausea; Cachexia; Sarcopenia; Anorexia Nervosa | Details | |
Dronabinol(Vertanical) | VER-01 | Phase 3 Clinical | Vertanical GmbH | Low Back Pain | Details |
cannabidiol (Cardiol Therapeutics) | Phase 3 Clinical | Cardiol Therapeutics Inc | Coronavirus Disease 2019 (COVID-19); Pericarditis; Cardiovascular Diseases; Myocarditis | Details | |
RG-7774 | RG-7774 | Phase 2 Clinical | F. Hoffmann-La Roche Ag | Diabetic Retinopathy | Details |
Etrinabdione | VCE-004; EHP-101; VCE-004.8 | Phase 2 Clinical | Vivacell Biotechnology, Emerald | Multiple Sclerosis, Relapsing-Remitting; Scleroderma, Diffuse; Peripheral Arterial Disease | Details |
ART-2713 | NEO-1940; ART-2713; ART27.13; AZD-1940 | Phase 2 Clinical | Astrazeneca Plc, Neomed Inc, Pfizer Inc | Weight Loss; Pain; Anorexia; Cachexia; Low Back Pain | Details |
C20T5 | C20T5 | Phase 2 Clinical | Murdoch Childrens Research Institute | Details | |
C12T12 | C12T12 | Phase 2 Clinical | Murdoch Childrens Research Institute | Details | |
Beta-Caryophyllene | Phase 2 Clinical | Hartford Hospital | Pain | Details | |
CNTX-6016 | CNTX-6016 | Phase 1 Clinical | C.H. Boehringer Sohn Ag & Co. Kg | Chronic Pain; Pain; Diabetic Neuropathies; Nociceptive Pain | Details |
ZYN-001 | ZYN-001 | Phase 1 Clinical | Zynerba Pharmaceuticals | Neuralgia; Fibromyalgia | Details |
Cannabidiol/hydroxychloroquine | IHL-675A; IHL-675 | Phase 1 Clinical | Incannex Healthcare Ltd | Arthritis, Rheumatoid; Respiratory Distress Syndrome, Adult | Details |
AAT-730 | AAT-730; RQ-00202730; OCT-461201 | Phase 1 Clinical | Pfizer Holding France Farevaamboise | Pain; Irritable Bowel Syndrome; Neuralgia, Postherpetic; Neuralgia | Details |
Atorvastatin Calcium Hydrate/Cannabidiol | Phase 1 Clinical | Indication Bioscience LLC | Coronary Disease; Dyslipidemias | Details | |
IPI 201(Isosceles Pharmaceuticals Inc ) | IPI-201 | Phase 1 Clinical | Pain, Postoperative | Details | |
HU-308 | PPP-003 | Phase 1 Clinical | Panag Pharma | Pain; Retinal Diseases; Uveitis; Xerophthalmia; Ocular inflammation | Details |
NTRX-07 | MDA7; NTRX-07; MDA-7 | Phase 1 Clinical | The University Of Texas MD Anderson Cancer Center | Alzheimer Disease; Neuralgia | Details |
MP-10X | MP-10X | Clinical | Medipure Holdings | Pain | Details |
Cannabidiol (Receptor Life Sciences) | Clinical | Receptor Life Sciences Inc | Autism Spectrum Disorder | Details | |
Cannabidiol/Palmitoylethanolamide | THX-210; SCI–210 | Clinical | Therapix Biosciences Ltd | Autism Spectrum Disorder; Diabetic Neuropathies | Details |
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