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This protein carries a polyhistidine tag at the C-terminus
The protein has a calculated MW of 24.6 kDa. The protein migrates as 25-27 kDa under reducing (R) condition (SDS-PAGE).
>95% as determined by SDS-PAGE.
Lyophilized from 0.22 μm filtered solution in 20 mM HEPES, 50 mM KCl, pH7.5 with trehalose as protectant.
Contact us for customized product form or formulation.
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
Human Bcl-x, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.
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English Name | Research Code | Research Phase | Company | First Brand Name | First Approved Country | First Indication | First Approved Company | First Approved Date | Indications | Clinical Trials |
---|---|---|---|---|---|---|---|---|---|---|
Gossypol acetic acid/Potassium Chloride/Vitamin B1/Vitamin B6 | Approved | Mainland China | Uterine Hemorrhage; Uterine Neoplasms; Endometriosis | Xi'An Beifang Medicine Co Ltd | 1988-01-01 | Endometriosis; Uterine Hemorrhage; Uterine Neoplasms | Details | |||
R-(-)-gossypol acetic acid | AT-101; BL-193; TW-37; NSC-726190 | Approved | University Of Michigan, Jiangsu Yasheng Pharmaceutical Development Co Ltd, National Institutes Of Health | Mainland China | Contraception; Genital Diseases, Female | Shanxi Panlong Pharmaceutical Group Limited By Share Ltd | 2002-01-01 | Esophageal Neoplasms; Contraception; Genital Diseases, Female; Glioblastoma; Lymphoma, Large B-Cell, Diffuse; Small Cell Lung Carcinoma; Hormone-Resistant Prostate Neoplasms; Adrenocortical Carcinoma; Lymphoma, Follicular; Lymphoma, Mantle-Cell; Brain Neoplasms; Gliosarcoma; Leukemia, Lymphocytic, Chronic, B-Cell | Details |
English Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
---|---|---|---|---|---|
Pelcitoclax | BM-1252; APG-1252; APG 1252 12A | Phase 2 Clinical | Jiangsu Yasheng Pharmaceutical Development Co Ltd | Solid tumours; Ovarian Neoplasms; Small Cell Lung Carcinoma; Neuroendocrine Tumors; Lymphoma, Extranodal NK-T-Cell; Peritoneal Neoplasms; Primary Myelofibrosis; Lymphoma, Non-Hodgkin; Fallopian Tube Neoplasms; Endometrial Neoplasms; Uterine Neoplasms; Carcinoma, Non-Small-Cell Lung | Details |
TGRX-814 | TGRX-814 | Phase 2 Clinical | Hematologic Neoplasms; Leukemia; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Lymphoma | Details | |
LP-118 | LP-118 | Phase 2 Clinical | Guangzhou Lupeng Pharmaceutical Co Ltd, Newave Pharmaceutical Inc | Leukemia; Solid tumours; Leukemia, Lymphoid; Leukemia, Myelomonocytic, Chronic; Myelodysplastic Syndromes; Neoplasms; Multiple Myeloma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Richter's Syndrome; Primary Myelofibrosis; Leukemia, Prolymphocytic, T-Cell; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Myelodysplastic-Myeloproliferative Diseases; Leukemia, Lymphocytic, Chronic, B-Cell | Details |
UBX-1325 | UBX-1325 | Phase 2 Clinical | Unity Biotechnology Inc, Ascentage Pharma Group International | Diabetic macular oedema; Macular Degeneration | Details |
Mirzotamab clezutoclax | ABBV-155 | Phase 1 Clinical | Abbvie Inc | Solid tumours | Details |
DT-2216 | DT-2216 | Phase 1 Clinical | University Of Florida, Dialectic Therapeutics Inc | Hematologic Neoplasms; Solid tumours | Details |
ABBV-637 | ABBV-637 | Phase 1 Clinical | Abbvie Inc | Solid tumours; Carcinoma, Non-Small-Cell Lung | Details |
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