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Designed under ISO 9001:2015 and ISO 13485:2016
Manufactured and QC tested under a GMP compliance factory
FDA DMF filed
Animal-Free materials
Beta-lactam materials free
Batch-to-batch consistency
Stringent quality control tests
No animal derived peptone and lactose used in production process
This protein carries no "tag".
The protein has a calculated MW of 17.5 kDa. The protein migrates as 18 kDa±3 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).
>95% as determined by SDS-PAGE.
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with protectants.
Contact us for customized product form or formulation.
This product is supplied and shipped with blue ice, please inquire the shipping cost.
Upon receipt, store it immediately at -20°C or lower for long term storage.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
GMP Human IL-1 beta Protein on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).
GMP Human IL-1 beta Protein (Cat. No. GMP-ILBH16) stimulates proliferation of D10.G4.1 cells. The specific activity of GMP Human IL-1 beta Protein is>5.00 x 10^7 IU/mg, which is calibrated against WHO International Standard INTERLEUKIN-1 BETA (IL-1ß, Human rDNA derived) (NIBSC code: 86/680) (QC tested).
The Cell based assay shows batch-to-batch consistency between Acro's GMP and PG IL-1beta.
ACROBiosystems GMP grade products are produced under a quality management system and in compliance with relevant guidelines: Ph. Eur General Chapter 5.2.12 Raw materials of biological origin for the production of cell-based and gene therapy medicinal products; USP<92>Growth Factors and Cytokines Used in Cell Therapy Manufacturing; USP<1043>Ancillary Materials for Cell, Gene, and Tissue-Engineered Products; ISO/TS 20399-1:2018, Biotechnology - Ancillary Materials Present During the Production of Cellular Therapeutic Products.
ACROBiosystems Quality Management System Contents:
Designed under ISO 9001:2015 and ISO 13485:2016, Manufactured and QC tested under a GMP compliance factory
Animal-Free materials
Materials purchased from the approved suppliers by QA
ISO 5 clean rooms and automatic filling equipment
Qualified personnel
Quality-related documents review and approve by QA
Fully batch production and control records
Equipment maintenance and calibration
Validation of analytical procedures
Stability studies conducted
Comprehensive regulatory support files
Request For Regulatory Support Files(RSF)
ACROBiosystems provide rigorous quality control tests (fully validated equipment, processes and test methods) on our GMP grade products to ensure that they meet stringent standards in terms of purity, safety, activity and inter-batch stability, and each bulk QC lot mainly contains the following specific information:
SDS-PAGE
Protein content
Endotoxin level
Residual Host Cell DNA content
Residual Host Cell Protein content
Biological activity analysis
Microbial testing
Mycoplasma testing
In vitro virus assay
Batch-to-batch consistency
Price(USD) : $595.00
Price(USD) :
Price(USD) :
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English Name | Research Code | Research Phase | Company | First Brand Name | First Approved Country | First Indication | First Approved Company | First Approved Date | Indications | Clinical Trials |
---|---|---|---|---|---|---|---|---|---|---|
Canakinumab | ACZ-885 | Approved | Novartis Pharma Ag | Ilaris | United States | Muckle-Wells Syndrome (MWS); Cryopyrin-Associated Periodic Syndromes | Novartis Pharma Ag | 2009-06-17 | Gout; Dry Eye Syndromes; Arthritis, Gouty; Cryopyrin-Associated Periodic Syndromes; Wet Macular Degeneration; Sarcoidosis, Pulmonary; Cognitive Dysfunction; Alzheimer Disease; Primary Myelofibrosis; Cardiovascular Diseases; Muscular Dystrophy, Duchenne; Urticaria; Hyperimmunoglobulin D syndrome; Pulmonary Disease, Chronic Obstructive; Lung Neoplasms; Inflammation; Diabetes Mellitus; Carcinoma, Non-Small-Cell Lung; Anemia, Sickle Cell; Thrombocythemia, Essential; Diabetic Retinopathy; Peripheral Arterial Disease; Aortic Aneurysm, Abdominal; Behcet Syndrome; Pyoderma Gangrenosum; Hepatitis, Alcoholic; Diabetes Mellitus, Type 1; Prediabetic State; Familial Mediterranean Fever; Mevalonate Kinase Deficiency; Anemia; Atherosclerosis; Schnitzler Syndrome; Polycythemia Vera; Diabetes Mellitus, Type 2; Polyarticular Juvenile Idiopathic Arthritis; Still's Disease, Adult-Onset; Myelodysplastic Syndromes; Arthritis, Rheumatoid; Coronavirus Disease 2019 (COVID-19); Vasculitis; Hereditary Autoinflammatory Diseases; Muckle- | Details |
PG-201 | PG-201 | Approved | Viromed | Layla | South Korea | Osteoarthritis | Pmg Pharm Co Ltd | 2012-01-01 | Osteoarthritis, Knee; Osteoarthritis | Details |
Edaravone/(+)-2-Decanol | SIM-071201 | Approved | Jiangsu Simcere Pharmaceutical Co Ltd | 三贝心, 三贝欣, 先必新, Sanbexin | Mainland China | Stroke | Nanjing Simcere Dongyuan Pharmaceutical Co Ltd | 2020-07-29 | Brain Infarction; Cerebral Hemorrhage; Stroke; Ischemic Stroke; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Cognition Disorders | Details |
Diacerein | KW-4800; SF-277; Art-50 | Approved | Cartivix, Fisiodar, Verboril, Art, 安必丁, Artrodar, Artrolyt | Metabolic Dysfunction-Associated Steatotic Liver Disease; Diabetes Mellitus, Type 2; Coronavirus Disease 2019 (COVID-19); Insulin Resistance; Epidermolysis Bullosa; Osteoarthritis, Knee; Diabetes Complications; Osteoarthritis; Obesity; Osteoarthritis, Hip; Diabetes Mellitus; Overweight | Details | |||||
Andrographolide/Sodium Hydrogen Sulfite | Approved | Bacterial Infections | Details | |||||||
Edaravone/(+)-2-Decanol (Yantai Yene/Simcere) | Y-2 | Approved | Yantai Yene Pharma Co Ltd, Simcere Pharmaceutical Group Ltd | Mainland China | Stroke | Jiangsu Simcere Pharmaceutical Co Ltd | 2024-12-01 | Intracranial Hemorrhages; Stroke; Cognitive Dysfunction | Details | |
Rilonacept | RGN-303; KPL-914 | Approved | Regeneron Pharmaceuticals Inc | Arcalyst, 炎朵 | United States | Cryopyrin-Associated Periodic Syndromes | Kiniksa Pharmaceuticals Ltd | 2008-02-27 | Arthritis, Juvenile; Inflammation; Scleroderma, Diffuse; Renal Insufficiency, Chronic; Gout; Urticaria; Vascular Diseases; Cryopyrin-Associated Periodic Syndromes; Hearing Loss, Sensorineural; Genetic Diseases, Inborn; Pericarditis; Diabetes Mellitus, Type 1; Coronary Artery Disease; Deficiency of interleukin-1 receptor antagonist; Scleroderma, Systemic; Muckle-Wells Syndrome (MWS); Sarcoidosis; Atherosclerosis; Schnitzler Syndrome; Anemia; Still's Disease, Adult-Onset; Familial Mediterranean Fever | Details |
Thalidomide | NSC-66847; NSC-527179; K-17; FPF-300; FPF300 | Approved | Celgene Corp | Talizer, Thalidomide Celgene, Thalidomide Pharmion, Synovir, Thalomid, Thaled | Mainland China | Leprosy, Lepromatous; Multiple Myeloma | Changzhou Pharmaceutical Factory | 1982-01-01 | Xerostomia; Colorectal Neoplasms; Neuroectodermal Tumors, Primitive; Prostatitis; Primary Myelofibrosis; Osteosarcoma; Cholangitis, Sclerosing; Lymphoma, Mantle-Cell; Lymphoma, Follicular; Adenocarcinoma, Clear Cell; Carcinoma, Adenosquamous; Epilepsy; Erythema Nodosum; Sarcoma; HIV Wasting Syndrome; Pancreatitis, Chronic; Sarcoma, Ewing; Arachnoiditis; Gastrointestinal Hemorrhage; Retinoblastoma; Prostatic Neoplasms; Endometriosis; Lung Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Vascular Malformations; Myelodysplastic-Myeloproliferative Diseases; Mycobacterium avium-intracellulare Infection; Amyotrophic Lateral Sclerosis; Carcinoma, Hepatocellular; Burning Mouth Syndrome; Stomatitis; Neoplasm Metastasis; Appendiceal Neoplasms; Tuberculosis; Lymphoma, Non-Hodgkin; Angiodysplasia; Pelvic Pain; Glioma; Waldenstrom Macroglobulinemia; Leprosy, Lepromatous; Endometrial Neoplasms; Uterine Neoplasms; Anemia, Sideroblastic; Ovarian Neoplasms; Gastric Antral Vascular Ectasia; Lupus Erythematosus, Discoid; Carc | Details |
English Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
---|---|---|---|---|---|
Ensereptide | PXL-01 | Phase 3 Clinical | Promore Pharma | Tissue Adhesions; Post-surgical adhesions; Cicatrix | Details |
Efprezimod alfa | CD24-Fc; HAS-CD24; CD24-Fc-IgG; MK-7110; MK7110 | Phase 3 Clinical | Oncoimmune Inc | HIV Infections; Hematopoietic stem cell transplantation (HSCT); Solid tumours; Leukemia; Graft vs Host Disease; Coronavirus Disease 2019 (COVID-19); Myelodysplastic Syndromes; Dyslipidemias; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Leukemia, Myeloid, Acute; Melanoma | Details |
Lutikizumab | ABT-981 | Phase 3 Clinical | Abbvie Inc | Colitis, Ulcerative; Osteoarthritis, Knee; Hidradenitis Suppurativa; Osteoarthritis; Crohn Disease; Dermatitis, Atopic | Details |
Goflikicept | RPH-104 | Phase 3 Clinical | Trpharm | Familial Mediterranean Fever; Still's Disease, Adult-Onset; Schnitzler Syndrome; ST Elevation Myocardial Infarction; Pancreatitis; Coronavirus Disease 2019 (COVID-19); Pericarditis; Arthritis, Gouty; Gout | Details |
Canakinumab biosimilar (GENERIUM Pharmaceuticals) | GNR-086 | Phase 3 Clinical | Generium Pharmaceuticals | Still's Disease, Adult-Onset; Arthritis, Juvenile | Details |
Recombinant humanized monoclonal antibody antiIL-1β(Cp Guojian) | SSGJ-613 | Phase 3 Clinical | Sunshine GuoJian Pharmaceutical (Shanghai) Co Ltd | Tumor necrosis factor receptor associated periodic syndrome; Arthritis, Juvenile; Arthritis, Gouty; Gout; Inflammation | Details |
MAS-825 | MAS-825; MAS825 | Phase 3 Clinical | Novartis Pharmaceuticals Corp | Enterocolitis; Coronavirus Disease 2019 (COVID-19); Coronary Disease; Autoimmune Lymphoproliferative Syndrome | Details |
AVTX-009 | FL-101; AVTX-009; LY-2189102 | Phase 2 Clinical | Eli Lilly And Company | Diabetes Mellitus, Type 2; Arthritis, Rheumatoid; Autoimmune Diseases; Urinary Bladder Neoplasms; Hidradenitis Suppurativa; Carcinoma, Non-Small-Cell Lung | Details |
CU-06 | CU-06-EYE; CU-06-IBD; CU-061004; Sac-1004; CU-06-ONCO; CU-06-HAE; CU06-1004 | Phase 2 Clinical | Curacle Co Ltd | Myocardial Infarction; Neoplasms; Lung Diseases; Stroke; Diabetic macular oedema; Colitis, Ulcerative; Crohn Disease; Macular Degeneration; Angioedemas, Hereditary; Diabetic Retinopathy | Details |
IL1-beta receptor antagonist Therapy(Hamlet BioPharma) | Phase 2 Clinical | Hamlet BioPharma AB | Cystitis; Pain | Details | |
Diacerein (TWi Biotechnology/Castle Creek Pharmaceuticals) | AC-201; AC-201 Controlled release tablet; AC-201 CR; AC-203; CCP 020; CCP-020 | Phase 2 Clinical | Twi Biotechnology Inc | Diabetes Mellitus, Type 2; Epidermolysis Bullosa Simplex; Epidermolysis Bullosa; Pemphigoid, Bullous; Epidermolysis Bullosa, Junctional; Gout; Arthritis; Epidermolysis Bullosa Dystrophica | Details |
Gevokizumab | XMA-005.2; AB-7; XOMA-052; S-78989; VPM-087; XMA-0052 | Phase 1 Clinical | Xoma Corp | Colonic Neoplasms; Behcet Syndrome; Labyrinth Diseases; Panuveitis; Osteoarthritis; Uveitis; Colorectal Neoplasms; Cryopyrin-Associated Periodic Syndromes; Arthritis, Rheumatoid; Acne Vulgaris; Hereditary Autoinflammatory Diseases; Stomach Neoplasms; Esophageal Neoplasms; Carcinoma, Renal Cell; Pyoderma Gangrenosum; Diabetes Mellitus, Type 2; Diabetes Mellitus, Type 1 | Details |
DLX-2323 | DLX-2323 | Phase 1 Clinical | Delenex Therapeutics Ag | Inflammation | Details |
Tavo-103 | Tavo103; Tavo-103; TAVO-103A; TAVO103A | Phase 1 Clinical | Tavotek Biotherapeutics (Hong Kong) Ltd | Details |
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