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| ID | Components | Size |
| RIPO-RWM010-C01 | Liver organoid Basal medium MM | 225ml |
| ID | Components | Size |
| RIPO-RWM010-1-C01 | Liver organoid Supplement MM-1 | 20ml |
| RIPO-RWM010-1-C02 | Liver organoid Supplement MM-2 | 5ml |
The unopened Box A is stable for 12 months from the date of manufacture if stored under 2-8°C.
The unopened Box B is stable for 12 months from the date of manufacture if stored under -20°C.
The opened kit should be stored according to components table.
Protocol Diagram of liver organoid differentiation.
H&E Staining of liver organoid.
The liver organoids show expression of hepatocytes (HFN4a), hepatobiliary tracts (CK19), Albumin (ALB) and vascular endothelial cell (CD31).
Pre-mature liver organoids show liver lobules-like structure.
Liver organoids show better performance than HepG2 cell line in terms of the expression of Albumin, CYP3A4, CYP1A2, CYP2C9, CYP7A1 and BSEP.
Liver organoid show response to Rifampicin treatment as indication by the increase fluorescence intensity of CYP3A4.
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