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Your Position: Home > Antibody > C11D5.3 scFv > C13-MY2010b

Monoclonal Anti-C11D5.3 scFv Antibody, Mouse IgG1 (3G8C1) (MALS verified)

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  • Source

    Monoclonal Anti-C11D5.3 scFv Antibody, Mouse IgG1 (3G8C1) is a Mouse monoclonal antibody recombinantly expressed from HEK293 cells.

  • Clone

    3G8C1

  • Species

    Mouse

  • Isotype

    Mouse IgG1 | Mouse kappa

  • Antibody Type

    Recombinant Monoclonal

  • Reactivity

    Mouse

  • Immunogen

    Recombinant Mouse C11D5.3 scFv derived from HEK293 cells.

  • Specificity

    Specifically recognizes the antigen-recognition domain of C11D5.3 derived CARs.

  • Application
    ApplicationRecommended Usage
    ELISA0.2-250 ng/mL
  • Purity

    >95% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Purification

    Protein A purified / Protein G purified

  • Formulation

    Supplied as 0.2 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Shipping

    This product is supplied and shipped with dry ice, please inquire the shipping cost.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 3 months under sterile conditions.
SDS-PAGE
C11D5.3 scFv SDS-PAGE

Monoclonal Anti-C11D5.3 scFv Antibody, Mouse IgG1 (3G8C1) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).

SEC-MALS
C11D5.3 scFv MALS images

The purity of Monoclonal Anti-C11D5.3 scFv Antibody, Mouse IgG1 (3G8C1) (Cat. No. C13-MY2010b) is more than 90% and the molecular weight of this protein is around 135-165 kDa verified by SEC-MALS.

Bioactivity-ELISA
 C11D5.3 scFv ELISA

Immobilized Mouse anti-BCMA scFv (C11D5.3), His Tag at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-C11D5.3 scFv Antibody, Mouse IgG1 (3G8C1) (Cat. No. C13-MY2010b) with a linear range of 0.2-8 ng/mL (QC tested).

  • Background
    C11D5.3 is an IgG1 mouse monoclonal antibody specific for BCMA, which is a target for the immunotherapy of multiple myeloma and lymphomas. C11D5.3 scFv is the most commonly used ectodomain componse of BCMA-specific CARs. So far, multiple reported CART BCMA trials contain the anti-BCMA scFv derived from C11D5.3, such as FDA approved CARs Abecma.
  • Clinical and Translational Updates

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ETA of in-stock products: 2 business days

Price(USD) : $724.00

Price(USD) : $2079.00

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