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Your Position: Home > Antibody > TNF-alpha > TNA-PFM494

PE-Labeled Monoclonal Anti-TNF-alpha Antibody, human IgG1 (16H5) (0.03% Proclin)

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  • Application
    Flow Cytometry.
  • Clone
    16H5
  • Species
    Mouse
  • Isotype
    Human IgG1 | Human Kappa
  • Specificity
    This product is a specific antibody specifically reacts with human TNF-alpha protein.
  • Immunogen

    Purified Human TNF-alpha Protein.

  • Conjugate

    PE

    Excitation Wavelength: 488 nm / 561 nm

    Emission Wavelength: 575 nm

  • Formulation

    Supplied as 0.2 μm filtered solution in PBS, pH7.4, 0.2% BSA, 0.03% Proclin300 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Storage

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. Store at 2° to 8°C.
    2. Do not use after the expiration date shown on the label.
  • Background
    Tumor necrosis factor alpha (TNFα) is a cytokine produced primarily by monocytes and macrophages. It is found in synovial cells and macrophages in the tissues.The primary role of TNFα is in the regulation of immune cells. TNFα is able to induce apoptotic cell death, to induce inflammation, and to inhibit tumorigenesis and viral replication. Dysregulation of TNFα production has been implicated in a variety of human diseases, including major depression, Alzheimer's disease and cancer. Recombinant TNFα is used as an immunostimulant under the INN tasonermin. TNFα can be produced ectopically in the setting of malignancy and parallels parathyroid hormone both in causing secondary hypercalcemia and in the cancers with which excessive production is associated.
  • Clinical and Translational Updates

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ETA of in-stock products: 2 business days

Price(USD) : $60.00

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Drug Development Status

  • Number of Launched Drugs:64 Details
  • Number of Drugs in Clinical Trials:71 Details
  • Latest Research Phase:Approved

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