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| Cat. No. | Species | Product Description | Structure | Purity | Feature |
|---|---|---|---|---|---|
| SMO-H52D3 | Human | Human SMO Protein, His,Flag Tag (Detergent) |  |
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| SMO-H52P3 | Human | Human SMO Full Length Protein (VLP) |
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Immobilized Human SMO Full Length Protein-VLP (Cat. No. SMO-H52P3) at 10 μg/mL (100 μL/well) can bind Anti-SMO antibody with a linear range of 0.01-2.5 μg/mL (QC tested).
| Name | Research Code | Research Phase | Company | First Brand Name | First Approved Country | First Indication | First Approved Company | First Approved Date | Indications | Clinical Trials |
|---|---|---|---|---|---|---|---|---|---|---|
| Sonidegib Diphosphate | LDE-225; NVP-LDE-225 | Approved | Novartis Pharma Ag | Odomzo, 奥昔朵 | United States | Carcinoma, Basal Cell | Sun Pharmaceutical Industries Ltd | 2015-07-24 | Primary Myelofibrosis; Graft vs Host Disease; Skin Neoplasms; Multiple Myeloma; Neuroblastoma; Basal Cell Nevus Syndrome; Breast Neoplasms; Thrombocytosis; Prostatic Neoplasms; Hepatic Insufficiency; Colorectal Neoplasms; Astrocytoma; Blood Platelet Disorders; Bone Marrow Diseases; Glioma; Leukemia, Myeloid, Acute; HR-positive breast cancer; Metastatic breast cancer; Carcinoma, Pancreatic Ductal; Lung Neoplasms; Thrombocythemia, Essential; Myelodysplastic-Myeloproliferative Diseases; Carcinoma, Hepatocellular; Hepatoblastoma; Medulloblastoma; Leukemia; Solid tumours; Rhabdomyosarcoma; Hematologic Neoplasms; Blood Coagulation Disorders; Hemorrhagic Disorders; Hematologic Diseases; Ovarian Neoplasms; Carcinoma, Basal Cell; Leukemia, Myelogenous, Chronic; Esophageal Neoplasms; Stomach Neoplasms; Polycythemia Vera; Glioblastoma; Triple Negative Breast Neoplasms; Leukemia, Myelomonocytic, Chronic; Myelodysplastic Syndromes; Pancreatic Neoplasms; Liver Cirrhosis; Myeloproliferative Disorders | Details |
| Glasdegib | PF-04; PF-4449913; PF-04449913 | Approved | Pfizer Inc | Daurismo | United States | Leukemia, Myeloid, Acute | Pfizer Inc | 2018-11-21 | Hematologic Neoplasms; Solid tumours; Renal Insufficiency; Myelodysplastic Syndromes; Leukemia, Myelomonocytic, Chronic; Graft vs Host Disease; Primary Myelofibrosis; Hepatic Insufficiency; Leukemia, Myeloid, Acute; Fasciitis | Details |
| Vismodegib | R-3616; RG-3616; GDC-0449 | Approved | Genentech Inc, F. Hoffmann-La Roche Ltd | Erivedge | United States | Carcinoma, Basal Cell | Genentech Inc | 2012-01-30 | Gastrointestinal Stromal Tumors; Liposarcoma; Sarcoma, Synovial; Basal Cell Nevus Syndrome; Chondrosarcoma, Extraskeletal Myxoid; Brain Neoplasms; Prostatic Neoplasms; Osteosarcoma; Sarcoma, Ewing; Breast Neoplasms; Sarcoma; Neurofibrosarcoma; Gliosarcoma; Colorectal Neoplasms; Chondrosarcoma, Clear Cell; Sarcoma, Alveolar Soft Part; Lymphoma, Non-Hodgkin; Lymphoma; Carcinoma, Pancreatic Ductal; Chondrosarcoma, Mesenchymal; Uterine Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Central Nervous System Lymphoma; Adenocarcinoma; Hemangioendothelioma, Epithelioid; Neuroectodermal Tumors, Primitive, Peripheral; Sarcoma, Kaposi; Desmoplastic Small Round Cell Tumor; Hematologic Neoplasms; Ovarian Neoplasms; Chondrosarcoma; Medulloblastoma; Fibrosarcoma; Leiomyosarcoma; Rhabdomyosarcoma; Carcinoma, Basal Cell; Esophageal Neoplasms; Stomach Neoplasms; Mesenchymoma; Carcinoma, Renal Cell; Hemangiosarcoma; Solid tumours; Graft vs Host Disease; Lymphoma, Large B-Cell, Diffuse; Skin Neoplasms; Odontogenic Cyst, Calcif | Details |
| Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
|---|---|---|---|---|---|
| Patidegib | SGT-610; BBP-009; FIN-5; IPI-926 | Phase 3 Clinical | Infinity Pharmaceuticals Inc | Head and Neck Neoplasms; Chondrosarcoma; Carcinoma, Basal Cell; Neoplasms; Pancreatic Neoplasms; Basal Cell Nevus Syndrome; Primary Myelofibrosis; Adenocarcinoma | Details |
| Taladegib | RXDX-109; ENV-IPF-101; ENV-ONC-101; LY-2940680; ENV-101 | Phase 2 Clinical | Eli Lilly And Company | Solid tumours; Rhabdomyosarcoma; Medulloblastoma; Idiopathic Pulmonary Fibrosis; Neoplasms; Small Cell Lung Carcinoma; Colonic Neoplasms; Lung Diseases, Interstitial; Sarcoma; Cholangiocarcinoma; Breast Neoplasms; Neoplasm Metastasis | Details |
| GT-1708F | GT-1708F; GT-1708; GT1708F | Phase 2 Clinical | Suzhou Koshine Biomedica Inc | Solid tumours; Hematologic Neoplasms; Idiopathic Pulmonary Fibrosis | Details |
| Cipromedegib | SHR-1539 | Phase 1 Clinical | Jiangsu Hengrui Medicine Co Ltd | Solid tumours | Details |
| ZSP-1602 | ZSP-1602 | Phase 1 Clinical | Guangdong Zhongsheng Pharmaceutical Co Ltd | Medulloblastoma; Stomach Neoplasms; Esophageal Neoplasms; Carcinoma, Basal Cell; Carcinoma; Glioblastoma; Small Cell Lung Carcinoma; Neoplasms; Pancreatic Neoplasms; Neuroendocrine Tumors; Glioma | Details |
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