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Virus-like particles(VLPs) are formed by self-assembly of envelop/capsid proteins from viruses. Membrane Proteins can be constituted in-situ with VLPs produced from HEK293 cell cultures. These VLPs concentrate conformationally intact membrane proteins directly on the cell surface and produce soluble, high-concentration proteins perfect for immunization and antibody screening.
The VLPs provide the display of properly folded membrane proteins in their native cellular membrane in a compact size of 100~300 nm diameter (similar to the size of most viruses) making it optimal targets for dendritic cells in vivo and surface attachment for phage display.
The VLPs are highly immunogenic, so the immunization strategy should be optimized (antigen dose, regimen and adjuvant).
Supplied as 0.2 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
This product is supplied and shipped with dry ice, please inquire the shipping cost.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
Immobilized Human SMO Full Length Protein-VLP (Cat. No. SMO-H52P3) at 10 μg/mL (100 μL/well) can bind Anti-SMO antibody with a linear range of 0.01-2.5 μg/mL (QC tested).
The mean peak Radius of VLP is 60-80 nm with more than 95% intensity as determined by dynamic light scattering (DLS).
Price(USD) : $620.00
Price(USD) : $1235.00
Price(USD) : $4305.00
Explore our catalog of therapeutic antibody solutions to find the right products for you! We are dedicated to delivering solutions designed to help you drive innovation and push the boundaries of what therapeutic antibodies can be.
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English Name | Research Code | Research Phase | Company | First Brand Name | First Approved Country | First Indication | First Approved Company | First Approved Date | Indications | Clinical Trials |
---|---|---|---|---|---|---|---|---|---|---|
Sonidegib Diphosphate | LDE-225; NVP-LDE-225 | Approved | Novartis Pharma Ag | Odomzo, 奥昔朵 | United States | Carcinoma, Basal Cell | Sun Pharmaceutical Industries Ltd | 2015-07-24 | Primary Myelofibrosis; Graft vs Host Disease; Skin Neoplasms; Multiple Myeloma; Neuroblastoma; Basal Cell Nevus Syndrome; Breast Neoplasms; Thrombocytosis; Prostatic Neoplasms; Hepatic Insufficiency; Colorectal Neoplasms; Astrocytoma; Blood Platelet Disorders; Bone Marrow Diseases; Glioma; Leukemia, Myeloid, Acute; HR-positive breast cancer; Metastatic breast cancer; Carcinoma, Pancreatic Ductal; Lung Neoplasms; Thrombocythemia, Essential; Myelodysplastic-Myeloproliferative Diseases; Carcinoma, Hepatocellular; Hepatoblastoma; Medulloblastoma; Leukemia; Solid tumours; Rhabdomyosarcoma; Hematologic Neoplasms; Blood Coagulation Disorders; Hemorrhagic Disorders; Hematologic Diseases; Ovarian Neoplasms; Carcinoma, Basal Cell; Leukemia, Myelogenous, Chronic; Esophageal Neoplasms; Stomach Neoplasms; Polycythemia Vera; Glioblastoma; Triple Negative Breast Neoplasms; Leukemia, Myelomonocytic, Chronic; Myelodysplastic Syndromes; Pancreatic Neoplasms; Liver Cirrhosis; Myeloproliferative Disorders | Details |
Glasdegib | PF-04; PF-4449913; PF-04449913 | Approved | Pfizer Inc | Daurismo | United States | Leukemia, Myeloid, Acute | Pfizer Inc | 2018-11-21 | Hematologic Neoplasms; Solid tumours; Renal Insufficiency; Myelodysplastic Syndromes; Leukemia, Myelomonocytic, Chronic; Graft vs Host Disease; Primary Myelofibrosis; Hepatic Insufficiency; Leukemia, Myeloid, Acute; Fasciitis | Details |
Vismodegib | R-3616; RG-3616; GDC-0449 | Approved | Genentech Inc, F. Hoffmann-La Roche Ltd | Erivedge | United States | Carcinoma, Basal Cell | Genentech Inc | 2012-01-30 | Gastrointestinal Stromal Tumors; Liposarcoma; Sarcoma, Synovial; Basal Cell Nevus Syndrome; Chondrosarcoma, Extraskeletal Myxoid; Brain Neoplasms; Prostatic Neoplasms; Osteosarcoma; Sarcoma, Ewing; Breast Neoplasms; Sarcoma; Neurofibrosarcoma; Gliosarcoma; Colorectal Neoplasms; Chondrosarcoma, Clear Cell; Sarcoma, Alveolar Soft Part; Lymphoma, Non-Hodgkin; Lymphoma; Carcinoma, Pancreatic Ductal; Chondrosarcoma, Mesenchymal; Uterine Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Central Nervous System Lymphoma; Adenocarcinoma; Hemangioendothelioma, Epithelioid; Neuroectodermal Tumors, Primitive, Peripheral; Sarcoma, Kaposi; Desmoplastic Small Round Cell Tumor; Hematologic Neoplasms; Ovarian Neoplasms; Chondrosarcoma; Medulloblastoma; Fibrosarcoma; Leiomyosarcoma; Rhabdomyosarcoma; Carcinoma, Basal Cell; Esophageal Neoplasms; Stomach Neoplasms; Mesenchymoma; Carcinoma, Renal Cell; Hemangiosarcoma; Solid tumours; Graft vs Host Disease; Lymphoma, Large B-Cell, Diffuse; Skin Neoplasms; Odontogenic Cyst, Calcif | Details |
English Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
---|---|---|---|---|---|
Patidegib | SGT-610; BBP-009; FIN-5; IPI-926 | Phase 3 Clinical | Infinity Pharmaceuticals Inc | Head and Neck Neoplasms; Chondrosarcoma; Carcinoma, Basal Cell; Neoplasms; Pancreatic Neoplasms; Basal Cell Nevus Syndrome; Primary Myelofibrosis; Adenocarcinoma | Details |
Taladegib | RXDX-109; ENV-IPF-101; ENV-ONC-101; LY-2940680; ENV-101 | Phase 2 Clinical | Eli Lilly And Company | Solid tumours; Rhabdomyosarcoma; Medulloblastoma; Idiopathic Pulmonary Fibrosis; Neoplasms; Small Cell Lung Carcinoma; Colonic Neoplasms; Lung Diseases, Interstitial; Sarcoma; Cholangiocarcinoma; Breast Neoplasms; Neoplasm Metastasis | Details |
GT-1708F | GT-1708F; GT-1708; GT1708F | Phase 2 Clinical | Suzhou Koshine Biomedica Inc | Solid tumours; Hematologic Neoplasms; Idiopathic Pulmonary Fibrosis | Details |
Cipromedegib | SHR-1539 | Phase 1 Clinical | Jiangsu Hengrui Medicine Co Ltd | Solid tumours | Details |
ZSP-1602 | ZSP-1602 | Phase 1 Clinical | Guangdong Zhongsheng Pharmaceutical Co Ltd | Medulloblastoma; Stomach Neoplasms; Esophageal Neoplasms; Carcinoma, Basal Cell; Carcinoma; Glioblastoma; Small Cell Lung Carcinoma; Neoplasms; Pancreatic Neoplasms; Neuroendocrine Tumors; Glioma | Details |
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